#stem #Science #biology #microbiology #cancer #hero #SouthKorea
Its looks like we have a benchtop cure for cancer
Phys.org · Molecular switch reverses cancerous transformation at the critical moment of transition
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The mRNA technology behind coronavirus vaccines is now being used to create bespoke vaccines for cancer patients.
"Cancer vaccines weren’t a proper field of research before the pandemic. There was nothing. Apart from one exception, pretty much every clinical trial had failed. With the pandemic, however, we proved that mRNA vaccines were possible.
mRNA cancer vaccines work by giving the body instructions to make a harmless piece of a cancer-related protein. This trains the immune system to recognize and attack cancer cells carrying that protein. Think of it like a training manual for security guards. The vaccine gives the immune system a guide on what cancer looks like, so it knows exactly who to watch for and remove.
Going from mRNA Covid vaccines to mRNA cancer vaccines is straightforward: same fridges, same protocol, same drug, just a different patient.
In the current trials, we do a biopsy of the patient, sequence the tissue, send it to the pharmaceutical company, and they design a personalized vaccine that’s bespoke to that patient’s cancer. That vaccine is not suitable for anyone else. It’s like science fiction.
The UK was ready. We had fridges and we had world-class manufacturing and research facilities. During the pandemic, we had proven we could open and deliver clinical trials fast. Also, the UK had established a genomic global lead with Genomics England and the 100,000 Genome Project. All doctors and nurses in this country are trained in genomics.
So the UK government signed two partnerships: one with BioNTech to provide 10,000 patients with access to personalized cancer treatments by 2030, and a 10-year investment with Moderna in an innovation and technology center with capacity to produce up to 250 million vaccines. The stars were aligned.
For many years, we believed that research is inherently slow. It used to take 20 years to get a drug to market. Most cancer patients, unfortunately, will succumb by the time a drug gets to market. We showed the world that it could be done in a year if you modernize your process, run parts of the process in parallel, and use digital tools.
We have a trial to stop skin cancer coming back after you cut it out. It’s now completed. We over-recruited again, just like every single one of the trials that we ran, and the trial finished one year ahead of schedule. That’s completely unheard of in cancer trials because they normally run over-long.
What will happen now is that, over the next six to 12 months, we will monitor the people in the trial and work out if there’s a difference between the people who took the cancer vaccine and the ones who didn’t. We’re hoping to have results by the end of the year or beginning of 2026. If it’s successful, we will have invented the first approved personalized mRNA vaccine, within only five years of the first licensed mRNA vaccine for Covid. That’s pretty impressive."
- Dr. Lennard Lee, UK National Health Service oncologist and medical director at the Ellison Institute of Technology in Oxford
https://www.wired.com/story/wired-health-lennard-lee-cancer-vaccines/
WIRED · Covid Vaccines Have Paved the Way for Cancer Vaccines
Pancreatic Cancer Hijacks Metabolic Switch. New Target for Treatment Identified
https://medicalxpress.com/news/2025-03-metabolic-pancreatic-cancer.html
#cancer #pancreas #health
medicalxpress.comA metabolic 'switch' that could help stop the spread of pancreatic cancerResearchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolic "switch" to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.
Researchers develop a highly specific alpha-emitting drug for metastatic melanoma. This targeted radiotherapy accumulates in melanoma cells while sparing healthy tissues, offering a promising new treatment
https://www.sciencedaily.com/releases/2025/03/250312124420.htm
#health #cancer #melanoma
Democratic Rep. Raúl M. Grijalva of Arizona dies at 77 https://www.byteseu.com/827807/ #AdelitaGrijalva #America #Arizona #ArizonaStateGovernment #AZStateWire #BarackObama #BernieSanders #Cancer #DavidSchweikert #DistrictOfColumbia #GeneralNews #GovernmentAndPolitics #HakeemJeffries #NotableDeaths #Politics #RalM.Grijalva #ReginaRomero #RubenGallego #SylvesterTurner #Tucson #UnitedStates #UnitedStatesHouseOfRepresentatives #UnitedStatesOfAmerica #US #USNews #USA #USANews #WashingtonNews
Bytes Europe · Democratic Rep. Raúl M. Grijalva of Arizona dies at 77WASHINGTON (AP) — Democratic Rep. Raúl M. Grijalva, a champion of environmental protections and progressive ideals who took on principled but often futile causes during a two-decade career in Congress, died Thursday.Grijalva, who was 77, had risen to chair the U.S. House Natural Resources Committee during his 12 terms representing southern Arizona, a powerful perch he used to shape the nation’s environmental policies. He was known for reliably going to bat for immigrants and Native American tribes, and for the bolo tie he wore at home in Tucson and in the Capitol in Washington.Grijalva died of complications from cancer treatment,
https://www.europesays.com/1911369/ Democratic Rep. Raúl M. Grijalva of Arizona dies at 77 #AdelitaGrijalva #america #arizona #ArizonaStateGovernment #AZStateWire #BarackObama #BernieSanders #cancer #DavidSchweikert #DistrictOfColumbia #GeneralNews #GovernmentAndPolitics #HakeemJeffries #NotableDeaths #Politics #RalM.Grijalva #ReginaRomero #RubenGallego #SylvesterTurner #Tucson #UnitedStates #UnitedStatesHouseOfRepresentatives #UnitedStatesOfAmerica #US #USNews #USTopics #USA #USANews #WashingtonNews
Impact of excessive alcohol consumption on digestive health https://www.byteseu.com/825831/ #alcohol #Cancer #carcinoma #Chronic #Cirrhosis #Colorectal #ColorectalCancer #Compound #DigestiveSystem #dna #EsophagealCancer #ethanol #Fibrosis #Gallstones #GastricCancer #gastroenterology #GastrointestinalTract #Genetic #Health #Inflammation #Liver #Metabolism #Pancreas #Pancreatitis #PublicHealth #Smoking #Steatosis
Bytes Europe · Impact of excessive alcohol consumption on digestive healthExcessive alcohol consumption is a significant public health concern, responsible for approximately 6% of all deaths and contributing to 5.1% of the global disease burden. Alcohol use is a major risk factor for over 200 diseases, including liver cirrhosis, pancreatitis, and esophageal cancer, with a particularly high incidence of gastrointestinal diseases. More than 50% of alcohol-related deaths are caused by gastrointestinal diseases, highlighting the importance of understanding how ethanol affects the digestive system. This review aims to provide an overview of ethanol metabolism and the diseases caused by alcohol consumption, with a focus on the liver, gastrointestinal tract, pancreas, and
Replied in thread
@stux @EUCommission this tariff is quite harmful to everyone involved.
A good side effect of this is it may result in people drinking alcohol beverages less. There is always the Yin/Yang.
Drinking #alcohol weakens your immune system and causes liver disease, heart disease, breast, liver, and colorectal #Cancer.
A recent study shows promise for a personalized mRNA vaccine to prevent pancreatic cancer recurrence, offering hope for patients and highlighting the potential of tailored cancer treatments. https://www.japantimes.co.jp/commentary/2025/03/13/world/cancer-vaccine-shows-hope/?utm_medium=Social&utm_source=mastodon #commentary #worldnews #cancer #pancreaticcancer #mrna #vaccines #health #medicine
The Japan Times · Pancreatic cancer vaccine shows hope. Make the investment.
David Bowie’s producer recalls their haunting final conversation https://www.inbella.com/948269/david-bowies-producer-recalls-their-haunting-final-conversation/ #albums #cancer #CelebritiesNews #CelebrityDeaths #DavidBowie #Entertainment #music #musicians #rock #RockAndRoll #RockAndRollHallOfFame #singers
Just added another 5km to my efforts to virtually conquer Australia’s five highest peaks while raising money for Canteen — go read the latest blog post and donate today!
#Australia #Canteen #Cancer #Running
https://www.fivepeaks.org.au/fundraisers/alexkidman/five-peaks-challenge
Scientists at KAIST have made a groundbreaking discovery in cancer treatment by reversing colon cancer cells back into normal ones instead of destroying them. This approach focuses on using digital twin technology to simulate & analyze gene interactions, identifying key molecular switches that trigger this transformation.
If further research supports these findings, it could revolutionize cancer therapy, providing new hope for patients worldwide.
Evil brother to Propaganda is Censorship.
"National Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval"
https://www.propublica.org/article/national-cancer-institute-flagged-topics-vaccines-autism-rfk-jr
Vaccines. Fluoride. Autism. Communications involving these and 20 other “controversial, high profile, or sensitive” topics will get extra scrutiny under Health Secretary Robert F. Kennedy Jr.
ProPublicaNational Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval
More from 
ProPublica
Propublica: National Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval
Vaccines. Fluoride. Autism. Communications involving these and 20 other “controversial, high profile, or sensitive” topics will get extra scrutiny
https://www.propublica.org/article/national-cancer-institute-flagged-topics-vaccines-autism-rfk-jr
ProPublicaNational Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval
More from ProPublica
"I don’t know what else to say. Hold each other close. Don’t forget the people who need our love and support. Reach out and say something you’ve needed to say. Even if it’s hard. Especially if it’s hard. There’s no other way to grow. No other way to feel the warmth."
Surviving Leviathan with Peter Gelderloos · Hold Us All Close
Woken up feeling under the weather again all part and parcel of what I am going through. Not helped by the feeling of being detached from the world again.
Rectal #Cancer Vanishes After Immunotherapy Trial, Now Classified as FDA Breakthrough Therapy https://theheartysoul.com/rectal-cancer-immunotherapy-treatment/
The Hearty Soul · Rectal Cancer Vanishes After Immunotherapy Trial, Now Classified as FDA Breakthrough TherapyA humble yet groundbreaking clinical trial at Memorial Sloan Kettering Cancer Center (MSK) has achieved unprecedented results in the treatment of rectal cancer, marking an incredible milestone in oncology. The trial, which utilized the immunotherapy drug dostarlimab (called Jemperli), demonstrated a 100% remission rate in patients with mismatch repair-deficient (MMRd) or microsatellite instability-high (MSI-H) rectal...
Just for change I woke up sleepy and had to sleep on settee again. All very frustrating as it would be nice to get up rested!
Go see "Tomatoes Tried to Kill Me But Banjos Saved My Life" if you get the chance. Keith Alessi is an inspiring storyteller, and proceeds support local causes:
"Through donations, including 100% of all artist fees, the show has raised over $970,000 as of March 2024 for various cancer, community, music, and theatre charities."
www.tomatoestriedtokillme.comTomatoes Tried to Kill Me | Home | Tomatoes Tried to Kill Me But Banjos Saved My Life | Award-Winning Performance | Cancer Resources | Music | Theatre Performance | Charitable Causes | Banjos saved my life showTomatoes Tried to Kill Me But Banjos Saved My Life isn’t just a show, it’s a cause. Keith Alessi provides an authentic true story through an award-winning musical performance and is sure to leave you feeling empowered, inspired, and ready to dust off your own long forgotten dreams.