How does this translate to recent claims of a "three sigma" result indicating biomolecules on exoplanets as possibly observed by JWST?
I don't know how the researchers define their significance, and it is probably a complicated procedure analyzing the spectrum, but still -
Let's call the observed result again "R", and the null hypothesis that there are NO biomolecules on the planet "F".
A three sigma result would usually mean
P(R|F)=0.003, or in other words, if there are no biomolecules, the observed result only has a probability of 0.003.
As above, to obtain the *probability that there are biomolecules on the exoplanet* is the backwards claim of P(F|R), and to obtain this number, we again have to do
0.003*P(F)/P(R), meaning that we have to mulitply by the a priori probability that exoplanets are devoid of this biomolecule, and divide by the general probability of observing such spectra. On this admittedly naive level of analysis, it becomes clear that in order to make a statement about the probability of biomolecules on the exoplanet after the recent JWST result, one needs to factor in knowledge or a priori assumptions about the prevalence of such molecules and confounding factors.
End of thread
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